PD. Dr.
Jörg Männer   

Phone: +49 (0)551 397032
Fax.: +49 (0)551 397043

Profile Research Publications
PD. Dr. Jörg Männer


Hiermeier F, Männer J. 2017.
Kinking and Torsion Can Significantly Improve the Efficiency of Valveless Pumping in Periodically Compressed Tubular Conduits. Implications for Understanding of the Form-Function Relationship of Embryonic Heart Tubes. J Cardiovasc Dev Dis 4. pii: E19. doi:10.3390/jcdd4040019.

Happel CM, Thrane L, Thommes J, Männer J, Yelbuz TM. (2011)
Integration of an optical coherence tomography (OCT) system into an examination incubator to facilitate in vivo imaging of cardiovascular development in higher vertebrate embryos under stable physiological conditions. Ann Anat. 193:425-435.

Happel CM, Thommes J, Thrane L, Männer J, Ortmeier T, Heimann B, Yelbuz TM. (2011)
Rotationally acquired four-dimensional optical coherence tomography (OCT) of embryonic chick hearts using retrospective gating on the central A-scan.J Biomed Optics. 16(9):096007; doi:10.1117/1.3622491.

Jahr M, Männer J. (2011)
Development of the venous pole of the heart in the frog Xenopus laevis: A morphological study with special focus on the development of the venoatrial connections. Dev Dyn. 240:1518-1527.

Happel CM, Klose C, Witton G, Angrisani GL, Wienecke S, Groos S, Bach FW, Bormann D, Männer J, Yelbuz TM. (2010)
Non-destructive, high-resolution 3-dimensional visualization of a cardiac defect in the chick embryo resembling complex heart defect in humans using micro-computed tomography: double outlet right ventricle with left juxtaposition of atrial appendages. Circulation. 122:e561-564.

Hassoun R, Schwartz P, Rath D, Viebahn C, Männer J. (2010)
Germ layer differentiation during early hindgut and cloaca formation in rabbit and pig embryos. J Anat. 217:665-678.

Männer J, Wessel A, Yelbuz TM. (2010)
How does the tubular embryonic heart work? Looking for the physical mechanism generating unidirectional blood flow in the valveless embryonic heart tube. Dev Dyn. 239:1035-1046. Review.

Schaefer IM, Männer J, Faber R, Loertzer H, Füzesi L, Seeliger S. (2010)
Giant umbilical cord edema caused by retrograde micturition through an open patent urachus. Pediatr Dev Pathol. 13:404-407.

Männer J, Thrane L, Norozi K, Yelbuz TM. (2009)
In vivo imaging of the cyclic changes in cross-sectional shape of the ventricular segment of pulsating embryonic chick hearts at stages 14 to 17: a contribution to the understanding of the ontogenesis of cardiac pumping function. Dev Dyn. 238:3273-3284.

Jahr M, Schlueter J, Brand T, Männer J. (2008)
Development of the proepicardium in Xenopus laevis. Dev Dyn. 237:3088-3096.

Männer J. (2009)
The anatomy of cardiac looping: a step towards the understanding of the morphogenesis of several forms of congenital cardiac malformations. Clin Anat. 22:21-35. Review.

Goering W, Adham IM, Pasche B, Männer J, Ochs M, Engel W, Zoll B. (2008)
Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice. Cytogenet Genome Res. 121:88-95.

Männer J, Thrane L, Norozi K, Yelbuz TM. (2008)
High-resolution in vivo imaging of the cross-sectional deformations of contracting embryonic heart loops using optical coherence tomography. Dev Dyn. 237:953-961.

Norozi K, Thrane L, Männer J, Pedersen F, Wolf I, Mottl-Link S, Meinzer HP, Wessel A, Yelbuz TM. (2008)
In vivo visualisation of coronary artery development by high-resolution optical coherence tomography. Heart. 94:130.

Zamora M, Männer J, Ruiz-Lozano P. (2007)
Epicardium-derived progenitor cells require beta-catenin for coronary artery formation. Proc Natl Acad Sci U S A. 104:18109-18114.

Misske J, Männer J, Yelbuz TM. (2007)
Does the stage 16 embryo in Hamburger-Hamilton's "Series of normal stages in the development of the chick embryo" have a potential "conotruncal" heart defect? Pediatr Cardiol. 28:263-266.

Orhan G, Baron S, Norozi K, Männer J, Hornung O, Blume H, Misske J, Heimann B, Wessel A, Yelbuz TM. (2007)
Construction and establishment of a new environmental chamber to study real-time cardiac development. Microsc Microanal. 13:204-210.

Männer J, Merkel N. (2007)
Early morphogenesis of the sinuatrial region of the chick heart: a contribution to the understanding of the pathogenesis of direct pulmonary venous connections to the right atrium and atrial septal defects in hearts with right isomerism of the atrial appendages. Anat Rec. 290:168-180.

Wilting J, Buttler K, Schulte I, Papoutsi M, Schweigerer L, Männer J. (2007)
The proepicardium delivers hemangioblasts but not lymphangioblasts to the developing heart. Dev Biol. 305:451-459.

Schulte I, Schlueter J, Abu-Issa R, Brand T, Männer J. (2007)
Morphological and molecular left-right asymmetries in the development of the proepicardium: a comparative analysis on mouse and chick embryos. Dev Dyn. 236:684-695.

Brade T, Männer J, Kühl M. (2006)
The role of Wnt signalling in cardiac development and tissue remodelling in the mature heart. Cardiovasc Res. 72:198-209. Review.

Männer J. (2006)
Extracardiac tissues and the epigenetic control of myocardial development in vertebrate embryos. Ann Anat. 188:199-212. Review.

Schlueter J, Männer J, Brand T. (2006)
BMP is an important regulator of proepicardial identity in the chick embryo. Dev Biol. 295:546-558.

Männer J. (2006)
Ontogenetic development of the helical heart: concepts and facts. Eur J Cardiothorac Surg. 29 (Suppl 1):S69-74. Review.

Boehm D, Laccone F, Burfeind P, Herold S, Schubert C, Zoll B, Männer J, Pauer HU, Bartels I. (2006)
Prenatal diagnosis of a large de novo terminal deletion of chromosome 11q. Prenat Diagn. 26:286-290.

Männer J, Kluth D. (2005)
The morphogenesis of the exstrophy-epispadias complex: a new concept based on observations made in early embryonic cases of cloacal exstrophy. Anat Embryol 210:51-57.

Männer J, Schlueter J, Brand T. (2005)
Experimental analyses of the function of the proepicardium using a new microsurgical procedure to induce loss-of-proepicardial-function in chick embryos. Dev Dyn. 233:1454-1463.

Mannan AU, Roussa E, Kraus C, Rickmann M, Maenner J, Nayernia K, Krieglstein K, Reis A, Engel W. (2004)
Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse. Neurogenetics. 5:229-238.

de Lange FJ, Moorman AF, Anderson RH, Männer J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM. (2004)
Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 95:645-654.

Männer J. (2004)
On rotation, torsion, lateralization, and handedness of the embryonic heart loop: new insights from a simulation model for the heart loop of chick embryos. Anat Rec A 278:481-492.

Männer J, Heinicke F. (2003)
A model for left juxtaposition of the atrial appendages in the chick. Cardiol Young. 13:152-160.

Männer J, Kluth D. (2003)
A chicken model to study the embryology of cloacal exstrophy. J Pediatr Surg. 38:678-681.

Männer J, Seidl W, Heinicke F, Hesse H. (2003)
Teratogenic effects of suramin on the chick embryo. Anat Embryol. 206:229-237.

Dathe V, Gamel A, Männer J, Brand-Saberi B, Christ B. (2002)
Morphological left-right asymmetry of Hensen's node precedes the asymmetric expression of Shh and Fgf8 in the chick embryo. Anat Embryol. 205:343-354.

Männer J.(2001)
On the value of morphogenetic classifications of hearts with double outlet right ventricle. Cardiol Young. 11:689-690.

Männer J. (2001)
Does an equivalent of the "ventral node" exist in chick embryos? A scanning electron microscopic study. Anat Embryol. 203:481-490.

Männer J, Pérez-Pomares JM, Macías D, Muñoz-Chápuli R. (2001)
The origin, formation and developmental significance of the epicardium: a review. Cells Tissues Organs.169:89-103. Review.

Männer J, Jakob C, Steding G, Füzesi L. (2001)
Horseshoe lung: report on a new variant--"inverted" horseshoe lung--with embryological reflections on the formal pathogenesis of horseshoe lungs. Ann Anat. 183:261-265.

Männer J. (2000)
Cardiac looping in the chick embryo: a morphological review with special reference to terminological and biomechanical aspects of the looping process. Anat Rec. 259:248-262. Review.

Männer J. (2000)
Embryology of congenital ventriculo-coronary communications: a study on quail-chick chimeras. Cardiol Young. 10:233-238.

Männer J. (1999)
Does the subepicardial mesenchyme contribute myocardioblasts to the myocardium of the chick embryo heart? A quail-chick chimera study tracing the fate of the epicardial primordium. Anat Rec. 255:212-226.

Männer J. (1998)
The origin and course of coronary vessels: embryological considerations. Cardiol Young. 8:534-535.

Männer J, Seidl W, Steding G. (1998)
Complete transposition in a chick embryo demonstrated by scanning electron microscopy. Cardiol Young. 8:396-399.

Männer J, Seidl W, Steding G. (1997) The formal pathogenesis of isolated common carotid or innominate arteries: the concept of malseptation of the aortic sac. Anat Embryol. 196:435-445.

Männer J, Seidl W, Steding G. (1997) Embryological observations on the formal pathogenesis of double-outlet left ventricle with a right-ventricular infundibulum. Thorac Cardiovasc Surg. 45:172-177.

Männer J, Seidl W, Steding G. (1996)
Experimental study on the significance of abnormal cardiac looping for the development of cardiovascular anomalies in neural crest-ablated chick embryos. Anat Embryol. 194:289-300.

Männer J, Seidl W, Steding G. (1995)
Embryological observations on the morphogenesis of double-outlet right ventricle with subaortic ventricular septal defect and normal arrangement of the great arteries. Thorac Cardiovasc Surg. 43:307-312.

Männer J, Seidl W, Steding G. (1995)
The role of extracardiac factors in normal and abnormal development of the chick embryo heart: cranial flexure and ventral thoracic wall. Anat Embryol. 191:61-72.

Männer J, Seidl W, Steding G. (1995)
Formation of the cervical flexure: an experimental study on chick embryos. Acta Anat. 152:1-10.

Männer J, Seidl W, Steding G. (1993)
Correlation between the embryonic head flexures and cardiac development. An experimental study in chick embryos. Anat Embryol. 188:269-285.

Männer J. (1993)
Experimental study on the formation of the epicardium in chick embryos. Anat Embryol. 187:281-289.

Männer J. (1992)
The development of pericardial villi in the chick embryo. Anat Embryol. 186:379-385.

Steding G, Xu JW, Seidl W, Männer J, Xia H. (1990)
Developmental aspects of the sinus valves and the sinus venosus septum of the right atrium in human embryos. Anat Embryol. 181:469-475.